The Blues will look to bounce back after two Premier League defeats as Tammy Abraham is likely to return, at least to the bench, for the home side.
So what better than a stat pack, courtesy of Opta, to bring you bragging rights against your mates and get you fired up for this one?
Here’s a look at six key facts and statistics prior to kick off:
He may have been a major success in the Championship in his first managerial job, but Chelsea boss Frank Lampard has lost all three of his meetings against Aston Villa.
His Derby side faced Villa on three occasions last season, including the play-off final at Wembley Stadium, and lost every single bloody time.
Pick on Someone Your Own Size
Chelsea have a track record of bullying Premier League new boys, having lost just one of their last 55 Premier League home games against newly-promoted sides (W44 D10).
Despite this, the Blues have drawn their last two such games, last going three without a win against promoted clubs at home in the top-flight in August 1991.
No Coming Back
Something that Chelsea need to sort out though, is their inability to come from behind in games.
The Londoners are yet to gain a single point from a losing position in the Premier League this season, losing all four games in which they’ve fallen behind.
Caught Off Guard
Something that Chelsea fans will rejoice in after reading the previous statistic is that their Wednesday opponents often struggle to hold a lead.
Aston Villa have dropped the most points from winning positions in the Premier League this season (13), and have won just one of the four away games they’ve led in (W1 D1 L2).
Scoring a goal of the month contender against Manchester United at the weekend, Aston Villa captain Jack Grealish has been involved in six goals in his last seven Premier League appearances (three goals, three assists).
If he continues his fine form, he may have a good chance of being selected for England’s Euro 2020 squad.
Top Four Phobia
Villa have picked up just one point from their last 39 available in away games against sides starting the day in the top four (W0 D1 L12).
Their last such victory was at Chelsea in December 2011, as Stephen Ireland rounded off a 3-1 win with a goal and an assist.